LymphedemaV1, Main, Exploration, bibRecord, 003C82

Anaplastic Kaposi's sarcoma: a study of eight patients

Identifieur interne : 003C82 ( Main/Exploration ); précédent : 003C81; suivant : 003C83

Anaplastic Kaposi's sarcoma: a study of eight patients

Auteurs : Athanasia Tourlaki [Italie] ; Sebastiano Recalcati [Italie] ; Vinicio Boneschi [Italie] ; Francesca Gaiani [Italie] ; Antonella Colombo [Italie] ; Roberta Mancuso [Italie] ; Lucia Brambilla [Italie]

Source :

EJD. European journal of dermatology [ 1167-1122 ] ; 2013.

RBID : Pascal:13-0244475

Descripteurs français

Pascal (Inist)
- Sarcome de Kaposi, Lymphoedème, Malade, Chimiothérapie, Homme, Pronostic, Dermatologie.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Chemotherapy, Dermatology, Human, Kaposi sarcoma, Lymphedema, Patient, Prognosis.

Abstract

Anaplastic Kaposi's sarcoma is a rare form of vascular tumor, clinically notable for its high local aggressiveness, propensity for deep invasion and increased metastatic capacity. This cancer arises in patients with a history of Kaposi's sarcoma (KS) and because of its rarity, few clinical data are available. To gain insight into this rare disease, we present eight cases of anaplastic KS which developed in eight out of 578 (1.4%) patients suffering from classic KS and followed in our department over a period of 30 years. Clinically, seven patients presented with deep tissue invasion. All the anaplastic cases underwent systemic chemotherapy and five received a non-conservative surgical therapy. Four (50%) out of the eight patients are now in complete remission, while three (37.5%) of them died of anaplastic Kaposi's sarcoma and one (12.5%) died of pneumonia after an excellent response to chemotherapy alone. Our findings suggest that in patients with anaplastic KS, non-conservative surgery associated with systemic chemotherapy may lead to complete remission, avoiding the poor outcome reported in previous cases.

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Anaplastic Kaposi's sarcoma is a rare form of vascular tumor, clinically notable for its high local aggressiveness, propensity for deep invasion and increased metastatic capacity. This cancer arises in patients with a history of Kaposi's sarcoma (KS) and because of its rarity, few clinical data are available. To gain insight into this rare disease, we present eight cases of anaplastic KS which developed in eight out of 578 (1.4%) patients suffering from classic KS and followed in our department over a period of 30 years. Clinically, seven patients presented with deep tissue invasion. All the anaplastic cases underwent systemic chemotherapy and five received a non-conservative surgical therapy. Four (50%) out of the eight patients are now in complete remission, while three (37.5%) of them died of anaplastic Kaposi's sarcoma and one (12.5%) died of pneumonia after an excellent response to chemotherapy alone. Our findings suggest that in patients with anaplastic KS, non-conservative surgery associated with systemic chemotherapy may lead to complete remission, avoiding the poor outcome reported in previous cases.</div>
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Anaplastic Kaposi's sarcoma: a study of eight patients

Anaplastic Kaposi's sarcoma: a study of eight patients

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri